The first asymmetric whole synthesis of conolidine was created by Micalizio and coworkers in 2011.[2] This synthetic route allows access to both enantiomer (mirror image) of conolidine by using an early enzymatic resolution. "We confirmed that conolidine binds to the newly determined opioid receptor ACKR3, although demonstrating no affinity https://is-conolidine-an-opiate55549.wssblogs.com/30885203/not-known-facts-about-conolidine