44 In addition, anergic cells Typically retain a greater susceptibility to apoptosis Unless of course anti-apoptotic proteins for instance BCL2 are overexpressed, as is the situation for CLL cells.forty five Certainly, most major therapeutic developments developing in the last decade are related to the inhibition of BCR and BCL2-mediated signaling. https://jamess356qoq9.wikiap.com/user