Tapentadol is partly metabolized by the hepatic enzymes CYP2C9, CYP2C19, and CYP2D6 so it innately has interactions with medications that enhance or repress the activity/expression of a number of of these enzymes, in addition to with substrates of these enzymes (as a consequence of competition for the enzyme); some enzyme https://henriky222xpg3.iamthewiki.com/user